CHERUBS - The Association of Congenital Diaphragmatic Hernia Research, Awareness and Support
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CDH
CDH Research
CHERUBS
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CHERUBS - The Association of Congenital Diaphragmatic Hernia Research, Awareness and Support
The History of Congenital Diaphragmatic Hernia
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Diaphragmatic Hernia was first described in 1575 by Pare' in reporting
in 2 autopsies of adults who had acquired diaphragmatic hernias by
trauma.
- In 1672, the first description of Congenital
Diaphragmatic Hernia was reported by Lazarus Riverius during the
autopsy of an adult male. Miraculously, this man lived 24 yrs with CDH
in the 17th century.
- In 1701, Holt reported the first case of CDH in a child.
- In 1796, Morgagni discussed various types of diaphragmatic hernia,
including the anterior CDH that bears his name.
- In 1827, Cooper described the symptoms, pathology and classification
of CDH.
- 1834 Laennec was the first to suggest a laparotomy that could be used
to withdraw intestine from the chest cavity.
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In 1847, Bowditch presented the first collected series of patients with
diaphragmatic hernia in 1847 before the Boston Society for Medical
Observation.
- In 1848, Bochdalek, described CDH that occurs posterolateral. This
now bears his name.
- In 1888, the first recorded attempt of a laparotomy to reduce the
hernia was made by Naumann.
- In 1902 the first reported successful operation of an infant born
with CDH
- In 1946, Robert Gross reported the first successful repair of a CDH
in a baby less than 24 hours old.
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In 1976, ECMO (Extracorporeal Membrane Oxygenation) was first used
successfully in the treatment of persistent pulmonary hypertension.
- In 1976, doctors first used lambs to create a CDH, researching for
the cause and best treatment of CDH.
- In 1989, Michael Harrison led the team at the UCSF in the first
succesful open fetal surgery for CDH.
- In 1992, "Gentle Ventilation" of CDH first began at the University of
Florida, led by David Kays
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In 1994, the first NIH sponsored clinical trial for fetal surgery was
done at UCSF for the open repair of congenital diaphragmatic hernia
- In 1995, The CDH Study Group was formed with medical professionals
from the around the world with a vested interest in CDH.
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In 1995, the first international organization for families and medical
care providers of children born with Congenital Diaphragmatic Hernia
was created. CHERUBS still leads the CDH community in providing support
and works with the medical committee to provide information and
research options.
- In 1996, first successful fetoscopic temporary tracheal occlusion for
CDH was done at UCSF by Harrison and team.
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In 1997, CHERUBS published it's first Congenital Diaphragmatic Hernia
Research Survey Results, tallying research data from families.
- In 1997, the first on-line information site for CDH was created by
CHERUBS.
- In 2000, First NIH sponsored randomized controlled trial for fetal
surgery was done at UCSF
- In 2000, the first international conference for families affected by
CDH was held in Orlando.
- In 2007, the Association of Congenital Diaphragmatic Hernia
Organizations (ACDHO) was formed.
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Also in 2007, the Official Congenital Diaphragmatic Hernia Awareness
Ribbon was created by families of children born with CDH to help raise
awareness and research of the birth defect.
- In 2007, the first on-line forum specificially for CDH was created
- In 2008, CHERUBS created the first web site dedicated solely to free
access of information for research of CDH.
- In 2009, the first CDH Conference with members of 6 CDH groups met in San Antonio, TX
- In 2010, CHERUBS launched the national "Save the Cherubs" Campaign
- In 2010, ACDHO created their first web site to help CDH families and CDH researchers to come together
- In 2010, CHERUBS launched the fight for 2 Congressional Bills to
raise CDH Research Funds and to protect the free right to raise CDH
Awareness
- Stonewall Jackson suffered from an unrepaired Diaphragmatic Hernia.
Whether it was Congenital is not known.
- CDH occurs in 1 of every 2500 to 4000 babies, as reported in 2006 by
The CDH Study Group. The survival rate is still 50%.
References:
A
population-based study of congenital diaphragmatic hernia. - Torfs CP, Curry CJ,
Bateson TF, Honoré LH.
California Birth Defects Monitoring Program,
Emeryville 94608.
Congenital
Diaphragmatic Hernia; Prem Puri; Current Problems in Surgery;
Volume XXI Number 10 October 1994
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